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CIPRO HC OTIC (ciprofloxacin hydrochloride and hydrocortisone otic suspension) contains the synthetic broad spectrum antibacterial agent, ciprofloxacin hydrochloride, combined with the anti-inflammatory corticosteroid, hydrocortisone, in a preserved, nonsterile suspension for otic use. Each mL of COPRO HC OTIC contains ciprofloxacin hydrochloride (equivalent to 2 mg ciprofloxacin), 10 mg hydrocortisone (equivalent to 2 mg ciprofloxacin), 10 mg hydrocortisone, and 9 ml benzyl alcohol as a preservative. The inactive ingredients are a polyvinyl alcohol, sodium chloride, sodium acetate, glacial acetic acid, phospholipon 90HB (modified lecithin), polysorbate, and purified water. Sodium hydroxide or hydrochloric acied may be added for adjustment of pH.
Ciprofloxacin, a fluoroquinolone, is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. Its empirical formula is C17-h18-FN3-O3-HCl-H2O.
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